Franco Salomon Clinical Study - London

The Effects of Treatment with Recombinant Human Growth Hormone on Body Composition and Metabolism in Adults with Growth Hormone Deficiency
Salomon, Franco; Cuneo RC; Hesp R.; Sönksen PH. ( 1989 )

This was a Double-Blind, Placebo-Controlled Clinical Trial to study the effects of using Growth Hormone ( GH ) replacement. They tested 24 adults over a time period of six months.

In 1989, Dr. Franco Salomon and his associates, in London, England, demonstrated that Human Growth Hormone ( HGH ) treatment given to this group of adults with deficient levels, over a span of six months, resulted in an increase in lean body mass of over 10% and a 7% reduction of body fat.

These subjects also experienced a significant increase in basal metabolic rate, as well as improved strength and exercise performance, which had previously been below normal. They took measurements after application of the GH at the end of one month and six months. But those in the placebo group had no significant changes in these markers.

Additionally, the fasting plasma cholesterol levels in the group of men and women who were given the Growth Hormone were also lower than those in the placebo group.

They concluded that Growth Hormone {GH} plays a role in regulating the composition in human bodies, most likely because of its anabolic and lipolytic actions.